Ionis Pharmaceuticals Inc. (IONS)
IONS trades on Nasdaq in Health Care, Biotechnology: Pharmaceutical Preparations. Numbers below come from the Nasdaq screener and SEC filings, each with its source.
Price · October 14, 2026
$42.38
-2.95% on the day
Market cap
$7.0B
Mid cap
Revenue · 2025
$943.7M
+33.8% on 2024
Net income · 2025
-$381.4M
-40.4% net margin
Price, change, market cap, sector and industry: Nasdaq stock screener, as of October 14, 2026. Revenue: SEC XBRL frames, calendar 2025.
Profile
| Field | Value |
|---|---|
| Ticker | IONS on Nasdaq |
| Sector | Health Care |
| Industry | Biotechnology: Pharmaceutical Preparations |
| Country | United States |
| IPO year | Not reported by the screener |
| SEC CIK | 0000874015 |
| SEC industry code | Pharmaceutical Preparations |
| Incorporated in | CA |
Financials · 2025
| Line | Value |
|---|---|
| Revenue | $943.7M |
| Net income | -$381.4M |
| Operating income | -$381.7M |
| Net margin | -40.4% |
| Operating margin | -40.4% |
| Revenue growth | +33.8% |
| Cash | $372.3M |
| Total assets | $3.5B |
| P/E (computed) | Net income was not positive |
| P/S (computed) | 7.5× |
Key SEC documents
| Document | Form | Filed |
|---|---|---|
| Latest prospectus or offering document | 424B5 | 2024-09-10 |
| Latest annual report IONIS PHARMACEUTICALS, INC. 10-K 12-31-2025 | 10-K | 2026-02-26 |
| Latest quarterly / interim IONIS PHARMACEUTICALS, INC. 10-Q 06-30-2026 | 10-Q | 2026-07-29 |
| Latest current report CURRENT REPORT FILING | 8-K | 2026-09-23 |
| Latest proxy | DEFA14A | 2026-04-23 |
Source: SEC EDGAR submissions feed, 1,000 recent filings. All filings on EDGAR.
Price moves
| Window | Return |
|---|---|
| 1 week | -3.3% |
| 1 month | -9.6% |
| 3 months | -21.9% |
| Year to date | -46.0% |
| 1 year | -39.5% |
| From 52-week high | -50.6% |
Source: Yahoo Finance daily closes, last bar 2026-10-14. Computed by Sophia Capital from daily closes; cap, sector and tier from the Nasdaq screener.
Peers in Biotechnology: Pharmaceutical Preparations
| Ticker | Company | Price | Day | Market cap |
|---|---|---|---|---|
| SYRE | Spyre Therapeutics Inc. | $80.45 | -6.34% | $7.1B |
| AMRX | Amneal Pharmaceuticals Inc. | $19.57 | -2.30% | $6.8B |
| PRAX | Praxis Precision Medicines Inc. | $243.34 | -3.20% | $6.8B |
| ALKS | Alkermes plc | $39.73 | -1.32% | $6.7B |
| ABVX | Abivax SA | $86.22 | -0.83% | $7.5B |
| KNSA | Kiniksa Pharmaceuticals International plc | $78.53 | -0.90% | $6.1B |
| BLTE | Belite Bio Inc | $151.87 | -4.24% | $6.1B |
| AXSM | Axsome Therapeutics Inc. | $156.32 | -5.83% | $8.2B |
The full dossier has every filing, three years of financials, private raises and the people who signed them.
Open the full dossier